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5F-ADB (also known as 5F-MDMB-PINACA) is an indaloze based synthetic cannabiniod from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic products and has been sold online as a designer 5F-ADB is a potent a of the cb rector,[ though it is unclear whether it is selective for this target. 5F-ADB was first identified in November 2014 from post-mort samples taken from an individual who had died after using a product containing this substance. Subsequent testing identified 5F-ADB to have been present in a total of ten people who had died from unexplained drug overdoses in Japan between September 2014 and December 2014. 5F-ADB is believed to be extremely potent based on the very low levels detected in tissue samples, and appears to be significantly more toxic than earlier synthetic cannabinoid drugs that had previously