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The use of OPANA ER is recommended for managing pain that is severe enough to necessitate daily, round-the-clock, long-term opioid treatment and for which no other available treatments are effective.

When a continuous, round-the-clock opioid analgesic is required for a prolonged period of time, Opana ER (oxymorphone hydrochloride extended-release tablets) was first approved in 2006.

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