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Duratia 60 mg contains the active ingredient Dapoxetine, which is used to treat premature ***** (PE) in men. It is classified as a selective serotonin reuptake inhibitor (SSRI), and its primary function is to help delay *****, improving ***** satisfaction and control. While Duratia 60 mg is effective for many men with premature *****, there are certain groups of people who should not use this medication due to potential health risks or adverse effects. Who Should Not Use Duratia 60 mg (Dapoxetine)? 1. Men with Heart Conditions: Heart disease: If you have a history of heart attack, heart failure, or other serious heart conditions, it is generally advised to avoid Duratia. SSRIs like Dapoxetine can affect the cardiovascular system, and people with heart issues may experience complications such as arrhythmias (irregular heartbeat) or low blood pressure. High or low blood pressure: Dapoxetine can cause changes in blood pressure, and men with high blood pressure (hypertension) or low blood pressure (hypotension) should be cautious or avoid using this medication. 2. Men Taking Nitrate Medications: Nitrates (e.g., nitroglycerin, isosorbide) are often used for chest pain (angina) or heart conditions. Combining Dapoxetine with nitrates can lead to a dangerous drop in blood pressure (hypotension), which can be life-threatening. Do not take Duratia if you are on nitrate medications. 3. Men with Liver Problems: If you have severe liver disease (such as cirrhosis or liver failure), you should not take Duratia 60 mg. Dapoxetine is metabolized by the liver, and impaired liver function can lead to an accumulation of the drug in your system, increasing the risk of side effects. 4. Men with Kidney Problems: Men with severe kidney disease or impaired renal function should avoid Duratia, as the drug may not be properly metabolized or cleared from the body, leading to higher blood concentrations and potential side effects. Mild to moderate kidney issues may still allow for the use of Duratia, but dosage adjustments and careful monitoring are necessary. 5. Men with Depression or Mental Health Conditions:

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